Bioanalytical Mass Spectrometry

Team Members

Oberacher Herbert, PhD, Priv.-Doz.
Oberacher Herbert, PhD, Priv.-Doz.
Oberacher Herbert, PhD, Priv.-Doz.

Phone: +43 512 9003 70630
herbert.oberacher@i-med.ac.at


Prof. Pavlic Marion, MD
Prof. Pavlic Marion, MD
Prof. Pavlic Marion, MD

Phone: +43 512 9003 70630
marion.pavlic@i-med.ac.at


Libiseller Kathrin, PhD
Libiseller Kathrin, PhD
Libiseller Kathrin, PhD

Phone: +43 512 9003 70630
kathrin.libiseller@i-med.ac.at


Beer Beate, MD
Beer Beate, MD
Beer Beate, MD

Phone: +43 512 9003 70630
beate.beer@i-med.ac.at


Schubert Birthe, PhD, MSc
Schubert Birthe, PhD, MSc
Schubert Birthe, PhD, MSc

Phone: +43 512 9003 70630
birthe.schubert@i-med.ac.at


Erb Robert, MSc
 
Erb Robert, MSc

Phone: +43 512 9003 70630
robert.erb@i-med.ac.at


Plattner Sabine, MSc
 
Plattner Sabine, MSc

Phone: +43 512 9003 70630
sabine.plattner@i-med.ac.at

 

Former Team Members

Monzo-Fuentes Alexandre, MSc
Pechriggl Claudia, MSc
Pitterl Florian, PhD, MSc

Research Topics

The research activities mainly focus on the analysis of (bio)organic molecules in particular on the analysis of small molecules (drugs, pharmaceuticals, metabolites) as well as on the analysis of nucleic acids. The method of choice for the characterization of these species is mass spectrometry, which is in most cases hyphenated to a chromatographic method (liquid chromatography and gas chromatography). Research activities are indented to optimize the complete analytical process. We are working on the optimization of chromatographic techniques, on the improvement of the mass spectrometric detection of biomolecules, on the validation of sample preparation procedures, and the application of the established techniques in fields like forensic analysis, environmental analysis, diagnostics, therapeutic drug monitoring, metabolic profiling, genetics, as well as pharmacogenetics.

Bioanalysis

Projects

  1. Analysis of nucleic acids with "ion-pair reversed phase high-performance liquid chromatography electrospray ionization mass spectrometry (ICEMS)"
  2. Tandem mass spectrometric sequencing of nucleic acids
  3. Development of a tandem mass spectrometric library for the identification of small molecules- "Wiley Registry of Tandem Mass Spectral Data, MSforID"
  4. Electrochemical simulation of oxidation reactions involving nucleic acids
  5. Metabolic profiling of pharmaceuticals
  6. Development and validation of analytical methods for drug monitoring
  7. Optimization of sample preparation techniques for the analysis of small molecules (SPE, SPME, SPDE, …)
  8. Pharmacogenetics

Assays

A number of immunochemistry, GC/MS as well as LC/MS assays are available for immediate application. A detailed list is provided here. For other targets (i.e. pharmaceutical compounds, drugs and metabolites thereof as well as genetic markers) an assay development service is provided. Please contact Herbert Oberacher for more information.

Collaboration partners

  1. G. Lorbeer, Österreichisches Umweltbundesamt
  2. E. Csaszar, Max F. Perutz Laboratories, University Departments at the Vienna Biocenter, Department of Biochemistry, University Vienna
  3. H. C. Köfeler, Core Facility for Mass Spectrometry & Chromatography, Centre for Medical Research, Medical University of Graz, Graz
  4. E. Deisenhammer, M. Defrancesco, Department of General Psychiatry, Innsbruck Medical University
  5. P. Oefner, Institute of Functional Genomics, University Regensburg
  6. R. Schuhmacher, M. Sulyok, Christian Doppler Laboratory for Mycotoxin Research, Department IFA-Tulln, University of Natural Resources and Applied Life Sciences, Vienna
  7. U. Griesser, Institute of Pharmacy, University of Innsbruck
  8. G. Stockhammer, M. Hutterer, Clinical Department of Neurology, Innsbruck Medical University
  9. T. Letzel, Competence Pool Weihenstephan, , Technische Universität München
  10. D.  Gjerde, PhyNexus Inc., San Jose, CA
  11. J.-P. Chervet, Antec, Leyden
  12. W. Weinmann, Institute of Forensic Medicine, Universitätsklinikum Freiburg
  13. U. Karst, Institut für Anorganische und Analytische Chemie, Westfälische Wilhelms-Universität Münster
  14. J. Josephs, S. Chacko, Bristol-Myers Squibb Company, Pennington, NJ
  15. F. Tagliaro, R. Gottardo, Unit of Forensic Medicine, Department Public Health and Community Medicine, University of Verona
  16. W. Weinmann, Institute of Forensic Medicine, University of Bern
  17. A. Amann, Labor der Universitätsklinik für Anästhesie und Intensivmedizin, Medizinische Universität Innsbruck
  18. A. Carracedo, Institute of Forensic Science-CIBERER, University of Santiago de Compostela
  19. I. Piatkov, Diversity Health Institute, Westmead Hospital
  20. A. Metspalu, K. Krjutškov, IMCB, University of Tartu
  21. A. Bernkop-Schnürch, K. Leithner, Institute of Pharmacy, University of Innsbruck
  22. M. Hubalek, Department of Obstetrics and Gynecology, Innsbruck Medical University
  23. B. Sperner-Unterweger, B. Holzner, A. Oberguggenberger, Department of Psychiatry and Psychotherapy, Innsbruck Medical University
  24. J. Marksteiner, Abteilung für Psychiatrie und Psychotherapie A, LKH Hall

Instrumentation

Job offers

We are always seeking for motivated and talented individuals with background in chemistry, pharmacy, biology, or medicine to join our team. To receive information on currently open positions please contact Herbert Oberacher.

GMI Tirol » Research » Bioanalytical Mass Spectrometry