Effect of cannabis use on cognitive functions and driving ability

Kurzthaler,I.; Hummer,M.; Miller,C.; Sperner-Unterweger,B.; Gunther,V.; Wechdorn,H.; Battista,H.J.; Fleischhacker,W.W.
BACKGROUND: Neither experimental nor epidemiologic approaches have so far given definitive answers to the question of the potential effect of cannabis on driving ability. METHOD: To shed more light on this topic, we conducted a placebo-controlled double-blind study including 60 healthy volunteers (a negative urine drug screening test was prerequisite). On the first day, baseline data were obtained from a physical examination and a psychological test battery for the investigation of visual and verbal memory as well as cognitive perceptual performance. On the second day, subjects received a regular cigarette or one containing 290 microg/kg body weight of tetrahydrocannabinol. Physical and psychological assessments were performed immediately (15 minutes) after subjects smoked their cigarettes. Twenty-four hours later, physical and psychological examinations were repeated. RESULTS AND CONCLUSION: Our results suggest that perceptual motor speed and accuracy, 2 very important parameters of driving ability, seem to be impaired immediately after cannabis consumption
J Clin Psychiatry 1999 60(6):395-399
Tags: 99328346; adult; adverse effects; Attention; Automobile Driving; chemically induced; Cognition; Cognition Disorders; complications; diagnosis; Double-Blind Method; drug effects; Euphoria; female; Headache; human; Libido; Light; male; Marijuana Abuse; Memory; Motor Skills; Nausea; Neuropsychological Tests; pharmacology; Physical Examination; Placebos; Psychiatric Status Rating Scales; psychology; Psychomotor Performance; statistics & numerical data; Tetrahydrocannabinol; urine
Home » Research » Publications » Detail